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Uji Aktivitas Anti-Osteoporosis dani Spilanthes Acmella dan Kombinasi Latihan Fisik pada Mencit yang Diinduksi Deksametason (The Study of Anti-Osteoporotic Activity of Spilanthes Acmella and Exercise Combination on Mice Dexamethasone Induced)

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ABSTRACT

Introduction: Spilanthes acmefla or which already knowby society as Legetan. is one of Indone¬sian medicinal plants In previous in vitro study, it was reported that 70% ethanol extract, buihanol and water.fractMn from this plant have increased alkaline phaspharase that brown as marker of bone formation. Aim. The objective of this in vivo study was to analysis the anti osteoporosis effect of Spilanthes acmella.

Method: This study using a post-test control group design, 60 male healthy mice which were randomizeo.devided into I °groups. There were healthy control group and osteoporosis groups. The osteoporosis group divided into positive control group (blendrona0,70% ethanol extract and physical exercise group. the combination of 70% extract ethanol and exercise, the hutanol. hexane, etil asetat and water fraction group. The study conducted for 4 weeks

Result Combined 70% ethanol extract Spilanthes Acmella with physical exercise significantly. increased trabeculor bone density greater than 70% ethanol extract without physical exercise.

Conclusion: It was proved that 70% ethanol extract ofSpilanthes acniella have are additive effect to physical exercise in osteoporotic condition.

Keyword: Spilanthes Genetic. osteoporosis, bone density

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

Journal of The Indonesian Medical Association, 64

Penerbit

Jakarta : Journal of the Medical Association., 2014

Deskripsi Fisik

7p

Bahasa

ISBN/ISSN

2089-1067

Klasifikasi

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Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

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Info Detail Spesifik

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Pernyataan Tanggungjawab

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Versi lain/terkait

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