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Paparan Ultraviolet C Meningkatkan Diameter Pulpa Alba Limpa dan Indeks Mitotik Epidermis Kulit Mencit (Ultraviolet C Exposure increases the White Pulp Diameter of Spleen and Epidermal Mitotic Index of Mice Skin)
ABSTRACT
This study aims to investigate the effects of ultraviolet Cexposure on the white pulp diameter of spleen and epidermal skin mitotic index of mice. An experimental study was performed in 5 groups, control and four treatment groups with exposure to ultravioletC in fourdifferent exposure time 15 (P1), 30 (P2), 60 (P3) and 120 minutes (P4)2 times a day for 15 consecutive days. Before treatment the mice back skin were shaved. On it day, mice were sacrificed, the back skin and spleen were prepared for histology slides to measure white pulp diameter of spleen and mitotic index skin epidermal of mice.
The result show that the lowest white pulp diameter of spleen was found in control group 380,241 61,91 and the highest is the P4 group = 586,00141,77. The lowest epidermal skin mitotic index was found in control group =9,70±2,27 and the highest is P4 group=38,2±3190. A one way ANOVA identify spleen white pulp diameter significant differences between groups (p
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