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Pengaruh Diet Sambal Tomat Ranti pada Struktur dan Fungsi Hepar Tikus yang Diinduksi Tawas (The Effect of "Sambal Tomat Ranti" on Structure and Function of Alum-induced Rat Liver)

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ABSTRACT

Indonesian has a habit of eating samba!, a kind of chili sauce that contains antioxidants. Exposedto free radicals, like alum which found on water or food will lead to structure and function damage of the liver. The aims of this research are to determine the effect of sambal tomat ranti (Lycopersicum pimpinellifolium Mill and Capsicum frutescens) on liver tissue and the levels of SGOT and SGPT on alum-induced rat. Laboratory experimental studies was performed with a control group post-test only design. Wistar strain Rattus novergicus, male, were divided into six groups:negotive control, positive control (8% alum-induced), ranti tomato 100% diet, combination of ranti tomato 100% with cayenne pepper 25%, 50% and 100%. The liver tissue was observed by counting the number of cellnecrosis. The liver function were observed based on the degree of transaminase (AST and ALT). Their elevation can provide some clues of liver damage. The test data analysis using One Way ANO VA, followed by post hoc test using the Least Significant Difference (LSD). Administratif of cayenne pepper can increase the number of hepaticceilnecrosis and increased levels of ASTand ALTsignificantly when compared to administration of ranti tomato only. Supplementation cayenne pepper induce structure and functional damage of alum Induced liver.

Keywords: Mum, cayenne pepper, chilli sauce, liver, tomato ranti

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

Jurnal Kedokteran Brawijaya 27 (3) 2013 : 156-162

Penerbit

Malang : Jurnal Kedokteran Brawijaya., 2013

Deskripsi Fisik

7p

Bahasa

ISBN/ISSN

2338-0772

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