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Efek Moringa olieferaterhadap Gula Darah dan Kolagen Matrik Ekstraseluler Sel βPankreas Diabetes Eksperimental (The Effect of Moringa oleifera on Blood Glucose and Collagen of Extra Cellular Matrix 13 Cell Pancreas on Diabetic Experiment)
ABSTRACT
Moringa defer° leaves contain bioactive substances which regenerate and stimulated cell pancreas for secreting insulin which regulates blood glucose levels. Survival and function of 8 cells need extra cellular matrix (ECM) namely fibronectin, laminin and collagen. Whether glucose level or ECM collagen which might be affected by streptozotocin harming 8 cell of pancreas was studied in experimental diabetes treated with M.oleifera.
This study used 24 rats. Blood glucose was measured before and after 2 days of streptozotocin induction confirming hyperglycemias, subsequently the rats were divided into 4 groups in which two control groups were terminated on day 0 and day 21 hyperglycemias, and two groups treated with M.oleifera leaf extract in dose of 250 and 500mg/kgBW/day for 21 days. Parametric and non parametric statistical analyses were used. Significance level is p
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