Pengaruh Iodium terhadap Perubahan Fungsi Tiroid dan Status Iodium/ | Perpustakaan Badan Kebijakan Pembangunan Kesehatan

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Pengaruh Iodium terhadap Perubahan Fungsi Tiroid dan Status Iodium/

Suryati Kumorowulan - Personal Name; Yusi Dwi Nurcahyani - Personal Name; Sri Kadarsih Soejono - Personal Name; Ahmad Hamim Sadewo - Personal Name;

Iodine is an essential element that enables the thyroid gland to produce thyroid hormones. The source of iodine in the body comes from food, iodized salt and iodine capsules. Iodized salt and iodine capsules had been used by the government in Iodine Deficiency Disorders (IDD) elimination program. However, iodine capsules prophylaxis program in the IDD endemic areas had caused symptoms of hyperthyroidism, subsequently the program was discontinued since 2009.

The aim of this research to determine the effect of iodine supplementation on thyroid function and iodine status. This was quasi-experimental design, conducted in Pituruh Purworejo District. Sample of this study consisted of 85 women of childbearing age, divided into three intervention groups. Each group obtained iodized salt for one month, then continued with the provision of iodized salt and 200 mg iodine capsules in group I, iodized salt and 400 mg iodine capsules in group II, and iodized salt and shredded tuna fish 2 times a week in group III for 3 months. Thyroid status was measured by levels of TSH, FT4 analyzed with ELISA. Iodine status measured by UIE levels analyzed with spectrophotometer. Data was analyzed using General Linear Model Repeated Measure (GLM RM). After 3 months, in all three treatment groups the TSH changes were statistically significant. In FT4 hormone levels, after administration of the intervention occurred “Wolff-Chaikoff” mechanism.

There were significant increase on Iodine status (UIE) (p< 0.05) in all three treatment groups. There is a change in iodine status and thyroid function after administration of three forms of iodine intervention.

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Location name is not set Media Gizi Mikro, 5(1) 2013: 17-29

A0004319

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Series Title: -
Call Number: Media Gizi Mikro, 5(1) 2013: 17-29
Publisher: Magelang : Balai Litbang Gangguan Aakibat Kekurangan Iodium., 2013
Collation: Media Gizi Mikro
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ISBN/ISSN: 2086-5198
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Subject(s): iodine
THYROID
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Statement of Responsibility: -

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