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Strategi Pengembangan Vaksin Dengue

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Dengue fever is a disease endemic in Indonesia. The disease is caused by dengue virus serotypes DENV1, DENV2, DENV3, and DENV4. One way to control the disease is dengue vaccine discovery.

This review based on the study of literatures that showed currently several strategies for dengue vaccine development are live attenuated vaccine, subunit vaccines, and DNA vaccines. Dengue vaccine development still face challenges, especially the formulation of vaccines that can trigger an immune response against all four serotypes and the absence of a suitable experimental animal. From all the existing strategies, the promising strategy is live attenuated vaccines using recombinant inter-flavivirus.

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Detail Information

Series Title

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Call Number

Junal Biotek Medisiana Indonesia, 2(2)2013: 43-49

Publisher

Jakarta : Pusat Biomedis dan Teknologi Dasar Kesehatan., 2013

Collation

Junal Biotek Medisiana Indonesia

Language

ISBN/ISSN

2301-5810

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Edition

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Subject(s)

DENGUE HEMORRHAGIC FEVER

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