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Faktor-Faktor yang Berhubungan dengan Eksaserbasi pada Pasien Penyakit ParuObstruktif Kronik di Rumah Sakit CiptoMangunkusumo, Jakarta

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ABSTRACT
Background: Chronic obstructive pulmonary disease (COP!)) exacerbation contributes to the severhy and progression ofCOP!). ills necesstoy to study on the factors associated with exacerbation of COP!) in Indonesia.
Objective: To determine the prevalence of COP!) evacerbations in Cipto Man gunkusumo Hospital (Chill). Jakarta during 2010 until 2012 and to identifyfactors associated with COPD exacerbation of patients in Calit

Methods: Crass-sectional study was carried on COP!) patients in Chill during 2010-2012. Clinical, supportive, and outcome data were obtained from medical records. Bivariate analysis was performed on age, history of smoking, comorbidity, severity of COPE), corticosteroid treatment, and frequency of exacerbations in past year. Eligible variables were then included in the multivariate analysis using logistic regression.

Results: A total of 184 patients enrolled in this study Prevalence of COPD exacerbation was 70.796. Pram bivariate amtlysis,severity ofC0PD, history ofsmoking,frequency of exacerbation in pram»; history of systemkcorticosteroid treatment, age, and comorbidity were eligible for multivariateanalysis. Significant independent risk factors included 22 times of COPD exacerbation in the previous year (OR 27.39: C195% 130-227,29; pv0.002), current smoker (OR 5.11; 095%1.07-24.35; p>0.04), grade 111 and IV COPD (OR 4.71; C195% 139-23.97; pr0.008), and comorbidity with Charlson Comorbld Index >2 (OR 4.09; C195% 1.37-12.18; p=0.01). Systemic cortico steroid is protective against COP!) exacerbation (OR 0.12; Cl 95% 0.03-0.54; p>0.01).

Conclusion: The premidence of COPD exacerbations in RSCM during 2010-2012 IV 70.7% Risk factors for COPD exacerbation included exacerbation in the previous year. current smoker grade III and IV COPD and comorbidity, while systemic corticosteroid is protectivefactor

Keywords: COPD exacerbation, risk factor, protective factor.

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

Indonesian Journal of CHEST, 1 (4) 2014 : 160-165

Penerbit

Jakarta : jo., 2014

Deskripsi Fisik

6p

Bahasa

ISBN/ISSN

2355-4584

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