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Mortality among Hospitalized HIV-Infected Patients with Tuberculosis in CiptoMangunkusumo Hospital, Jakarta, Indonesia: A Retrospective Cohort Study

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ABSTRACT

Background: Indonesia is the world's fourth highest tuberculosis (TB) burden in the world TB is the second leading cause of death feral! age In the country. Mortality rate remains high among hospitalized TB patients compared to the non-TB patients. The risk of death is significantly higher in HIV-infected patients with tuberculosis (TB). This the leading killer of HIV-infected individuals worldwide.

Objective: To describe the characteristics and to determine mortality rate among hospitalized HIV-infected patients with TB in Cipto Mangunimsumo Hospital (CMH), Jakarta, Indonesia.

Methods:A retrospective cohort study was performed among hospitalized TB/HIV patients in CMH between January2008 and September 2013. Data were collected or initiation ofInpatients period and the main outcome was all-cause mortality during hospitalization. Analyzed factors included age, sex, history of previous anti-TB treatment sputum smear positivity, hypoalbuminaniq BM1, pulmonary radiographic lesion and comorbidity (CCI score). Data were analyzed using Chi-square test or Fischer test.

Results: A total of 191 TB/H1V patients were evaluated In this study. There were 157 (82.6%) mole and 34(17.4%) female patients. Median age was 31 (range 20 to 71)years old and median lengthof stay was 11 (raqge 1 to 57)days. In-hospital mortality rate was 29,8%. One hundred and thirty patients had CD4 count data and 128 (98,5%)of them had CD4

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Indonesian Journal of CHEST, 1 (3) 2014 : 120-125

Publisher

Jakarta : Indonesian Journal of Chest., 2014

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6p

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2355-4584

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