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Tinjauan Imunologi Pneumonia pada Pasien Geriatri (Immunologic Aspects of Pneumonia in Geriatrics)

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ABSTRACT

Pneumonia becomes one of the major nealtn problems in the elderly. A characteristic of pneumonia in geriatric patients is its typicalclinical presentation. Immunological status changes due to the aging process to give an important consequence of the pulmonary fungtional reserve ability to cope with decreased lung compliance and increased airway resistance to irfection.Thymus involution due to aging decreases naive T cels production, changes memory T cel function, shifts tne cytokine profile from th1 to th2. In humorial immunity, there are decrease of B cells and its receptors, decrease of germinal center formation, dysfungtional generation of primary B lymphocytes, impaired memory B cell production, and increase of autoantibodies. Management includes antibiotic therapy and considerations for ICU treatment, and prevention of further infection..

Key words: gelatric, immunology. Pneumonia

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

Cermin Dunia Kedokteran, 41 (1) 2014: 14-18

Penerbit

: Kalbe Farma., 2014

Deskripsi Fisik

5p

Bahasa

ISBN/ISSN

0125-913x

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Tipe Media

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Tipe Pembawa

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Edisi

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