Efek Ekstrak Air dan Heksan Herba Suruhan Peperomia pellucida (L) Kunth) terhadap Penurunan Kadar Asam Urat Serum Darah Ayam Kampung Jantan | Perpustakaan Badan Kebijakan Pembangunan Kesehatan

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Efek Ekstrak Air dan Heksan Herba Suruhan Peperomia pellucida (L) Kunth) terhadap Penurunan Kadar Asam Urat Serum Darah Ayam Kampung Jantan

Nanang Yunarto - Personal Name;

One of the plants that had been used by the local people as a choice of traditional medicine for gout is suruhan (Peperomia pellucida (L) Kunth). This research was conducted to examine the effects of water and hexan extract of suruhan to decrease uric acid levels in cock. 40 cock made hyperuricemia with the administration combination of chicken liver juice 4 ml / kg and urea 1 mg / kg for 12 days. The test animals were divided into 8 groups. Group I as a negative control with administration of polyvinyl pyrrolidone (PVP) 0.5%. Group II was given allopurinol 10 mg/Kg BW as a positive control, a group III-V were given water extract 100; 200; 400 mg / Kg BW and group VI-VIII were given hexane extract 100; 200; 400 mg/Kg BW. Treatment begins day 13 to 20. On day 15, 18 and 21 were taken blood serum by vena lateralis wing vein to measure levels of uric acid, and calculated the percentage reduction in uric acid levels. From the result of pre clinic study on day 21, water extract of suruhan at the dose of 200 mg/Kg BW the highest decrease uric acid level about 62,49±2,80% and the highest decrease uric acid level with hexane extract is 19,62±3,95% at the dose of 400 mg/Kg BW. Potential water extract of suruhan 200 mg / kg BW is equivalent with Allopurinol 10 mg/kg BW. Water and hexan extract of suruhan has potency to decrease uric acid level that indicating the contain some chemical constituents in suruhan that possibly lead development to antihyperuricemia drug.

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Location name is not set Media Litbang Kesehatan, 23(1): 8-14

A0004149

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Series Title: -
Call Number: Media Litbang Kesehatan, 23(1): 8-14
Publisher: Jakarta : ., 2013
Collation: -
Language
ISBN/ISSN: 0853-9987
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Edition: -
Subject(s): PLANTS, MEDICINE
URIC ACID
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