Text

Hormon Tiroid dan Efeknya pada Jantung (Thyroid Hormor e and its Effect on the Heart)

---

ABSTRACT

Thyroid hormone is essential for maintaining structure and function of the heart. In normal condition, thyroid hormone preserves the strength of heart contraction (inotropy) to meet physiological demand.Thyroid diseases, either hyperthyroidism or hypothyroidism, cause pathologic heart abnormalities called thyroid heart diseases. The patologic heart abnormalities due to thyroid hormone disorders are dysrythmia, left ventricular hypertrophy and heart failure. The mechanism of action of thyroid hormone includes genomic and non-genomic types on cardiomyocyte that give short and long term phenotypic effects to the heart. Genomic effect includes modification of gene transcription in cardiomyocyte, whereas non-genomic effect includes ligation to membrane receptors and cytoplasmic proteins of cardiomyocytes.

Key words: thyroid hormone, cardiomyocyte, thyroid receptor

---

Availability

Detail Information

Series Title

-

Call Number

CDK:Cermin Dunia Kedokteran, 40 (9) 2013: 4p.

Publisher

: Kalbe Farma., 2013

Collation

4p

Language

ISBN/ISSN

0125-913x

Classification

-

Content Type

-

Media Type

-

Carrier Type

-

Edition

-

Subject(s)

-

Specific Detail Info

-

Statement of Responsibility

-

Other version/related

File Attachment

Comments

---

You must be logged in to post a comment