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Serum Adiponectin Level is Lower in Patients with Endometriotic Cyst (Tingkat Adiponektin Serum Lebih Rendah pada Pasien dengan Kista Endometriosis)
Abstract
Objectives: To analyse the difference of serum adiponectin level between patients with endometriotic cyst and those with non-en¬dometriotic cyst, and its difference between endometriosis stages.
Methods: This is a cross-sectional comparative analytical study in¬volving 25 women with endometriotic cyst and 25 women with non¬endometriotic cyst, which had undergone laparoscopy or laparo¬tomy surgery. Blood samples were withdrawn and checked for se¬rum adiponectin level in PRODIA laboratory in Jakarta. Serum adiponectin level of both groups were then measured and com¬pared. The study was conducted in Dr. Hasan Sadikin Hospital in September- December 2012.
Results: Shows no significant difference in subjects' characteristic which are age (p = 0.994) and BMI (p = 0.267). There is a significant difference (p < 0.0001) between serum adiponectin level in en¬dometriosis group (mean = 3.91 ± 1.976) with level of which in non¬endometriosis group (mean = 8.59 ± 1.977). There is no significant difference (p = 0.384) of serum adiponectin level between stage III endometriosis (mean = 4.24 ± 1.8168) and stage IV endometriosis (mean = 3.54 ± 2.1531).
Conclusion: Serum adiponectin level in patients with endometriotic cyst is significantly lower compared to level of which in patients with non-endometriotic cyst. There is no significant difference of serum adiponectin level between endometriosis stages.
[Indones J Obstet Gynecol 2013; 1-3: 119-23]
Keywords: adiponectin, endometriotic cyst, non-endometriotic cyst, endometriosis stage
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