Tenascin-C is Strongly Expressed in the Anterior Vaginal Walls of Women with Pelvic Organ Prolapse (Tenascin-C Diekspresikan dengan Kuat pada Dinding Vagina Anterior Perempuan dengan Prolaps Organ Panggu) | Perpustakaan Badan Kebijakan Pembangunan Kesehatan

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Tenascin-C is Strongly Expressed in the Anterior Vaginal Walls of Women with Pelvic Organ Prolapse (Tenascin-C Diekspresikan dengan Kuat pada Dinding Vagina Anterior Perempuan dengan Prolaps Organ Panggu)

Risma N Sulham - Personal Name; Trika Irianta - Personal Name; Umar Malinta - Personal Name;

Objectives: To compare the expression of tenascin in the anterior vaginal wall in women with pelvic organ prolapse and without pelvic organ prolapse (POP).

Method: This study was a cross sectional study. The study was con¬ducted in RS Dr. Wahidin Sudirohusodo and other network hospitals of Obstetrics and Gynecology Department of Hasanuddin University, Makassar, from 1st January 2011 to 1st April 2012. This study as¬sessed the expression of tenascin in 35 women with pelvic organ prolapse grade Ill and IV and the controls were 35 women without pelvic organ prolapse. Tenascin expression was assessed by immu¬nohistochemical examination using tenascin antibody staining (mouse monoclonal antibody Novacastratenascin C, code NCL¬TenasC). Sampling was done by consecutive sampling. Data proc¬essed by the chi-square. The significance level used was 0.05.

Result: The result of this research shows that with exception of his¬tory of bearing baby > 4000 gr weight (p=0.572); age, parity, meno¬pausal status, and body mass index were significantly different be¬tween the group. This indicates that the variable does not affect the calculation of research data. While parity, menopausal status and body mass index (BMI), from an analysis of risk factors for POP were associated with increased intensity of tenascin is significant in post¬menopausal status, and BMI >25 (overweight) (p

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Location name is not set Indonesian Journal of Obstetrict and Gynecology, 1

A0003888

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Series Title: -
Call Number: Indonesian Journal of Obstetrict and Gynecology, 1
Publisher: Jakarta : Indonesian Society of Obstetetrict and Gynecology., 2013
Collation: 6p
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ISBN/ISSN: 2338-6401
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