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Pengaruh Pemberian Produk "X" Yang Mengandung Ekstrak Daun Murbei (Morus Alba L.) Terhadap Kadar Trigliserida Pada Tikus Jantan Galur Wistar (The Effect of "X" Product Which Containing Of Murberry Leaves Extract (Morus alba L.) on Triglycerides Level of Male Wistar Rats

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ABSTRACT
Mulberry (Moms alba L.) is one of the source of a herbal medicine. The leaf has been reported as could reduces triglycerides level. Quercetin in mulberry leaves induces triglycerides catabolism to fatty acid and glycerol, and induces fatty acid oxidation to energy. The aim of this study is to know effect of pruduct "X" which contained mulberry leaves extract on the triglycerides of male Wistar rats. This study used 25 laboratory male Wistar rats, of 2-3 months age and 150-200 grams in body weight Twenty five rats were a divided into five groups at randomly: group A as the normal control group, group B as negative control group was fed a high-fat diet, group C as the solvent control group was given 0.5% CMC-Na, group D as the positive control was given gemfibrozil 126 mg / KgBW, and group E was given "X" product 630 mg/KgBW. Each group, which orally were fed the treatment for 7 days. The triglycerides level was checked on day 8 used an easy touch. The data of triglycerides level was obtained and analyzed statistically by ANOVA test with a confidence level 95%. The result showed, that the groups that given "X" product at a dose of 630 mg/KgBW and gemfibrozil dose 126 mg/KgBW in seven days, significanly decrease triglycerides level 9,45% (p

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FARMASAINS: Jurnal Ilmiah Ilmu-ilmu Kefarmasian, 2

Publisher

Jakarta : Jurusan Farmasi Uhamka Jakarta., 2013

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4p

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2086-6968

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