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Vascular Endothelial Growth Factor Air Mata sebagai Faktor Risiko Tumbuh Ulang Pterygium
Abstract
Introduction: The recurrence of pterygium is a major post-surgerycal problem. Surgical tech¬niques and Vascular Endothelial Growth Factor (VEGF) are thought to have influence on this phenomenon. The aim of the study was to analyze the role of VEGF as riskfactor to the pterygium recurrence.
Methods: The study design is a nested case control study. The total number of samples with 53 patients with a total of 56 eyes. A number of 56 eyes operated on using the technique of limbal conjunctival Autograft (CLAG) technique using fibrin glue. Examination of Enzyme-linked
Imrnunosorbent Assay (ELISA) was performed on 30 eyes, while 26 eyes had not do periodic checks for various reasons.
Results: Of the 30 eyes were examined by ELISA, the results obtained by 23 eyes with high VEGF levels with 20 of them having pterygium regrowth. Meanwhile, the seven eyes with low VEGF levels, four of which are experiencing regrowth.
Conclusion: Based on these results, we can conclude that the tears levels of VEGF that the tears level of VEGF are not significance to the eccurence of pterygium regrowth.
Keywords: Pterygium, recurrence, VEGF level
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