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Comparison of quantitative C-reactive protein concertration and cryptococus neoformans antigen detection results in patiens with human immunodeficiency virus
Cryptococcus neoformans infection is one of the opportunistic infections in HIV patients, it caused cryptococcal meningitis, which can be detected earlier using the antigen contained in the polysacharide capsule. The availability of this antigen test is very limited that other parameter are needed for early detection of cryptococcal meningitis. That parameter is C-Reactive Protein (CRP). The aim of this study was to compare the levels of quantitative CRP with the C. neoformans antigen detection in HIV patients. This was a comparative analytical study design using serum taken from HIV patients who came to the Teratai clinic RSUP dr. Hasan Sadikin Bandung. The sample inclusion criteria was, subject was on their first detection, having CD45.8197 mg/dL and 2 (14.3%) with CRP _5.5.8197 mg/dL. Conclusion: Quantitative CRP could be considered as a parameter for early detection of cryptococcal meningitis in HIV patients, by eliminating the possibilities that can lead to increased level of CRP.
Key words: C-Reactive Protein, Cryptococcal Antigen Latex Agglutination System, cryptococcal meningitis,
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