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DHF Cases Dominated by Den-3 Serotype in the West Java Province

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Although West Java is one of the endemic provinces for DHF in Indonesia, data on the distribution of serotypes in the province is still very limited to specifi c areas within different time periods. In 2000 – 2002, the serotype Den-2 dominated the Bandung city area. The purpose of this study was to identify the distribution of dengue virus serotype in the West Java province and the dominant serotypes in DHF cases.

Data was collected in October-December 2008 from 27 hospitals in the West Java province. The population for this study was all patients diagnosed with dengue virus hospitalized in the 27 hospitals. Sample was purposively chosen from these patients who were willing to participate in further immunologic examinations. Serum from patients who were immunologically positive was further examined to determine the dengue virus serotype. This examination was done in the Biomedical and Basic Health Technology Center of the Health Research and Development Unit Republic of Indonesia using the nested RT-PCR method.

Out 513 samples examined, 180 samples could be identifi ed. Dengue virus was not found in the rest of the samples. Four samples showed multiple infections of 2 dengue virus serotypes. All four serotypes were found in the West Java province. In all positive samples, Den-3 was found to be the dominant serotype with 47.8%, followed by Den-2 (26.0%), Den-1 (18.6%), Den-4 (5.4%), and mixed (2.2%). Den-3 was found in all endemic areas of the West Java province.

All 4 dengue virus serotypes can be found in the West Java province with Den-3 serotype the most dominant. (Health Science Indones 2012;1:23-6)

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Detail Information

Series Title

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Call Number

Health Science Journal of Indonesia, 3 (1) 2012: 2

Publisher

Jakarta : Sekretariat Badan Litbangkes., 2012

Collation

4p.

Language

English

ISBN/ISSN

2087-7021

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Edition

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Subject(s)

DENGUE HEMORRHAGIC FEVER

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