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Membran Sel Neuron Dan Sawar Darah Otak Sebagai Struktur Proteksi Otak (Membrane Neuronal Cell And Blood Brain Barrier As Structure Brain Protection
The brain is the body's vital organs are susceptible to damage. Have a high oxygen demand, is highly dependent on glucose, has a high metabolic rate, but have low adaptability of the injury and it is very difficult to regeneration. Injury on brain cells (neurons) is a serious condition because of risk for dysfunction and cells death.
The brain needsfor oxygen and glycogen constanly to produce the body's energy in the form of adenosine- 5'-triposphate (ATP) which is useful for maintaining life. Injury can interfere with the metabolism of these cells, reducing the production of ATP, reducing ATP reserves and cause glycolysis process in the body and the use of lactate as an energy source metabolisme.
This pathological condition for the occurrence of dam age cell and trigger to cell death through necrosis or apoptosis process. Therefore, the protective structure cell membran and cerebral vascular system su ch as special, the vascular structure is blood brain barrier.
Keywords: brain, neurons, cell membrane, blood brain barrier
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