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Perbandingan Penentuan Kadar Thyroid Stimulating Hormone (Tsh) Dengan Bloodspot Dan Dengan Tsh Serum Untuk Diagnosis Hipotiroidisme Pada Balita (Comparison Between The Use of Bloodspot Thyroid Stimulating Hormone (TSH) and TSH Serum for Under Five Hypothyroidism Diagnosis)

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lndonesia still has the congenital hypothyroidism Prevalence of 0.33% which is considered as high. The gold standard for the diagnosis on these cases in children under five years old is by the measurement of TSH serum. However, the screening of these cases in newborn can be used by the measurement of bloodspot TSH. The latest method has many benefits which are easier, more convenient and cheaper. To develop bloodspot method to diagnose hypothyroidism for Indonesian children under five years old.
This study was done at BP2GAKI clinic in and five public health center in Magelang region for the period of six months. This is a cross sectional non intervention research. The subject is children under five years old, suspected of hypothyroidism The measured of TSH bloodspot and TSH serum was done simultaneously. The validity of TSH bloodspot against TSH serum was analysis using crosstab. From the diagnostic tes TSH serum when compared to TSH bloodspot showed Sensitivity of 25 %; Specifity of 100%; while Positive Predictive Value was 100% and Negative Predictive Value was 93 %;. TSH serum Positive Likelihood Ratio was - and Negative Likelihood Ratio was 0.75. It is suggested to use TSH serum to diagnose thyroid function in children under five years old. Examination of TSH serum cannot be replaced by bloodspot TSH to diagnose hypothyroidism in children under five years old.
Keywords: Bloodspot TSH, serum TSH, hypothyroidism, children.

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

Media Gizi Mikro Indonesia, 3 (2) 2012 : 41-48

Penerbit

Jakarta : BP GAKI Magelang., 2012

Deskripsi Fisik

8p

Bahasa

ISBN/ISSN

2086-5198

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Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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