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Induksi Polifenol Mahkota Dewa dan Apoptosis Sel Kanker Paru Mencit Strain Balb/C:Analisis pada Up-Regulation Bax dan Down-Regulation Bcl-2 (Mahkota Dewa polyphenol induction and apoptosis cell lung cancer in Balblc strain mice analysis on up-regulation bax and down-regulation Bcl-2)

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Background: This research is aimed to prove the role of Mahkota Dewa polyphenol in the up-regulation Bax and down-regulation in strain Balblc mice which inducted with benzo(a)pyrene (BaP).
Method: Post test control group design with 30 strain Balblc mice sample, aged 1-2 weeks, weighed 20-30 grams, healthy mice condition. All mice inducted with BaP and then randomized into 2 groups, which were the control group and the treatment group (polyphenol 50 mg). The development of the lung carcinogenesis was observed by tissue surgery in the 8th, 17th and 26th week. The data collected inelude expression examination Bax and Bcl-2. The data analysis was conducted by Kruskal-Wallis, Mann-Whitney and correlation test of Spearman's with significance degree of p

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Series Title

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Call Number

et.al.-- Media Medika Indonesiana, 46 (1) 2012 : 3

Publisher

: FK Diponegoro Semarang., 2012

Collation

11p

Language

ISBN/ISSN

0126-1762

Classification

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Content Type

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Media Type

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Carrier Type

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Edition

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Subject(s)

plants, medicinal
lung neoplasms
APOPTOSIS

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Statement of Responsibility

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