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Malaria Detection using Polymerase Chain Reaction (PCR) Method in Pregnant Women's Saliva on Several Hospitals in North Sulawesi Province Deteksi Malaria dengan Metode peR pada Saliva Perempuan Hamil di Beberapa Rumah Sakit di Provinsi Sulawesi Utara

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Objective: To detect malaria by PCR examination of saliva in preg-nant women and to obtain the incidence of malaria and the type of plasmodium causing malaria in pregnant women at various hospital in North Sulawesi.
Method: A descriptive cross sectional study in pregnant women during antenatal care at the Department of Obstetri cs and Gynecology Faculty of Medicine University of Sam Ratulangi/Prof. Dr. R.D. Kandou General Hospital in Manado, R.W. Monginsidi Hospital in Manado, Bethesda Hospital in Tomohon, and Datoe Binangkang Hospital in Kotamobagu, from 1 April until 31 May 2008.
Result: There were 43 pregnant women ciinically diagnosed with malaria, 23 (53.49%) by PCR examination of saliva and 20 (46.59%) by blood smears. From 23 cases of malaria in pregnancy detected by PCR, there were 18 diagnosed as tropical malaria, 3 tertian malaria, and 2 mixed malaria.
Conclusions: The incidenee of malaria in pregnancy at various hospital in North Sulawesi using PCR methods for saliva examination from April 1 - May 31 2008 is 53.49%. In this study malaria are mostly caused by Plasmodium falciparum with the largest incidence in primigravida, in the first trim ester.
Keywords: malaria, PCR, pregnancy, saliva

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Indonesian Journal of Obstetrics and Gynecology, 3

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Jakarta : Universitas Padjadjaran Bag. Obstetri \r Ginekologi, Badan Litbangkes., 2012

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6p

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0303-7924

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