Text

39. Uji Diagnostik Pemeriksaan Tulang Osteolitik Berbasis Intensitas Citra Digital (Diagnostic test of osteolytic bone examination based on digital image intensity)

---

Background: The visual examination of bone radiographs using digital computed radiography (CR) is an examination for the diagnosis of bone-metastatic cancer. The subjectivity of interpretation of bone radiographs mcry lead to doctor's doubt in making decision to treatment patients with bone-metastatic cancer. Software Matlab-based computer application program makes a standard method to organize the results of bone radiographs. The objective of this study is to develop a software based on Matlab to analyze the diagnostic values, and to determine the optimal of cut off point to diagnose of osteolytic bone.
Method: The research es data are collectedfrom Department of Radiology ofthree hospitals i.e. Dr. Kariadi Hospital Semarang, Dr. Sardjito Hospital and Bethesda Hospital Yogyakarta. This research was carried out during four month from April to August 2009. Radiographs of osteolytic bone interpreted by radiologist were compared with PA examination result of the osteolytic bone which were viewed as the gold standard The steps in this study i.e. patients are classified as a normal or osteolytic bone patients based on the cut offpoint that had been determined, calculate the value of the diagnostic test using 2x2 tables, determined the area under the curve (AUC) by the procedure of receiver operating characteristic (ROC), and determined the optimal of cut offpoint.
Result: The results of study show that the diagnostic test for osteolytic bone by using Matlab-based software has sensitivity of o. 88, specificity of o. 891, positive expected value of 0.897, negative expected value of 0.950 and the cut off point at 0.93, while, the value of area under the curve (AUC) is 94% (95% CI: 89.7-98.3%), and the accuracy is 0.881 for the case of osteolytic bone.
Conclusion: Matlab-based software being usedfor diagnosing osteolytic bone has relatively high sensitivity and specijicity.
Keywords: Digital image, bone metastases, osteolytic, optimum cut offpoint

---

Availability

Detail Information

Series Title

-

Call Number

Media Medika Indonesiana, 46 (1) 2012 : 19-24

Publisher

Surabaya : FKG Universitas Airlangga Surabaya., 2012

Collation

6p

Language

ISBN/ISSN

0126-1762

Classification

-

Content Type

-

Media Type

-

Carrier Type

-

Edition

-

Subject(s)

bone and bones
OSTEOLYSIS

Specific Detail Info

-

Statement of Responsibility

-

Other version/related

File Attachment

Comments

---

You must be logged in to post a comment