Pajanan Pestisida Sebagai Faktor Risiko Hipotiroidisme pada Wanita Usia Subur di Daerah Pertanian (Pesticide exposure as a riskfactor for hypothyroidism in womef? at childbearing age in agricultural areas | Perpustakaan dan Galeri Kebijakan Kesehatan

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Pajanan Pestisida Sebagai Faktor Risiko Hipotiroidisme pada Wanita Usia Subur di Daerah Pertanian (Pesticide exposure as a riskfactor for hypothyroidism in womef? at childbearing age in agricultural areas

Suhartono - Nama Orang; RRJ Sri Djokomoeljanto - Nama Orang; Suharyo Hadisaputro - Nama Orang; Hertanto Wahyu Subagio - Nama Orang; Apoina Kartini - Nama Orang; Suratman - Nama Orang;

Background: Hypothyroidism in women at childbearing age (WCA) will cause reproduction disorder, i.e. infertility, spontaneous abortion, impaired growth and development of foetus, placental abruption, and preterm delivery. Pesticide exposure is suspected to cause hypothyroidism. The research objective is to prove that pesticide exposure is a risk factor for hypothyroidism among WCA in agricultural areas.
Methods: Case-control studies were used as study designs. Study subjects were 44 WCA as cases and 45 WCA as controls. Pesticide exposure was measured by asking WCA 's involvement in agricultural activities using structured questionnaire and by checking their levels of cholinesterase. Hypothyroidism was determined based on the results of TSH, FT4, and T3 level. Confounding variables were also measured. These variables were age, body mass index (BMI), participation in hormonal contraception, liver function, urinary iodine excretion, urinary thiocyanate level and blood lead level. Chi-square test, OR (95% CI), and multivariate logistic regression were implemented to test the hypothesis.
Results: Pesticides exposure is a risk factor for hypothyroidism (crude-OR=3.04; 95% CI=1.20-7.81; nilai p=0.033 and adjusted OR=3.31, 95% CI=1.25 to 8.78, p=0.016). The higher the degree of exposure, the greater the risk ofhaving hypothyroidism. Conclusion: Pesticides exposure is a riskfactor for hypothyroidism among WCA in agricultural areas.
Keywords: Pesticide exposure, riskfactor, hypothyroidism, women at childbearing age, agricultural area

Ketersediaan

Belum memasukkan lokasi Media Medika Indonesiana, 46 (2) 2012 : 91-99

A0003378

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Judul Seri: -
No. Panggil: Media Medika Indonesiana, 46 (2) 2012 : 91-99
Penerbit: Semarang : FK Diponegoro Semarang., 2012
Deskripsi Fisik: 9p
Bahasa
ISBN/ISSN: 0126-1762
Klasifikasi: -
Tipe Isi: -
Tipe Media: -
Tipe Pembawa: -
Edisi: -
Subjek: women
hypothyroidism
PESTICIDES
Info Detail Spesifik: -
Pernyataan Tanggungjawab: -

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