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The diagnostic value of fine needle aspiration biopsy and ultrasonography on thyroid nodule in Dr. Sardjito General Hospital, Yogyakarta

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As the prevalence of thyroid cancer increases, a diagnostic method that can identify malignancy that warrants further surgical treatment is needed . Fine needie aspiration bio psy (FNAB) and ultrasonography (USG) are preoperative test for diagnosing thyroid tumor. This research aimed to calculate the diagnostic value of FNAB and USG on thyroid nodule patients in Dr. Sardjito General Hospital, Yogyakarta.
This was a diagnostic test study using a retrospective design using data from medical records of patients with thyroid nodules from January 2006 to December 2010. The diagnositic value of FNAB and USG including sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy were calculated and compared with histopathological examination as the gold standard. Ninety medical records data of patients consisting of 71 females and 19 males who were diagnosed thyroid nodule with FNAB or USG before surgery were evaluated in this study.
The results of FNAB of 90 patients were as folIows: 54 (60.0%) benign, 6 (6.7%) malignant, and 30 (33.3%) follicular neoplasm. Meanwhile, the results USG of 90 patients were as tollows: 38 (42.2%) benign, 15 (16.7%) malignant and 37 (41.1%) non determined. The diagnostic value of FNAB was described as folIows: sensitivity of 50.0%, specificity of 100%, PPV of 100%, NPV of 50.0% and an accuracy of 60.0%, whereas the diagnostic value of USG was described as folIows: sensitivity of 81.8%, specificity of 87.5%, PPV 60%, NPV 94.5% and accuracy of 50.0%. In conclusion, the diagnostic value of FNAB and USG in establishing diagnosis of thyroid nodule is still low. The FNAB has higher accuracy compared to USG for diagnosing thyroid nodules.

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Detail Information

Series Title

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Call Number

Journal of the Medical Sciences, 44 (2) 2012 : 158

Publisher

Yogyakarta : FK Universitas Gajah Mada Yogyakarta., 2012

Collation

6p

Language

ISBN/ISSN

0126-1312

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Edition

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Subject(s)

ultrasonography
biopsy
THYROID NODULE

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