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Pengaruh Kitosan Terhadap Sifat Elongasi Dan Kekuatan Regang Biomembran Penutup Luka (The Influence of Chitosan on Elongation and Tensile Strength Characteristic of Wound Healing Biomembrane)

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Formulation of wound-healing chitosan biomembrane has been performed. The aim of the research was study the influence of chitosan solution on the elongation and tensile strength characteristic of the biomembrane. The degree of deecetytetion and the molecular weight were determined using IR spectroscopy and viscometry methode. Chitosan 4% solution within lactic acid 2% was formulated as biomembrane with honey, PVA, and glycerol were 10, 5, and 4% respectively. This formula was divided info 6 based on the volume of chitosan 4% solution 20, 25, 30, 35, 40% with honey and 40% without honey. The elongation and tensile strength of biomembrane were evaluated by universal testing machine and pH of biomembrane by pH meter. Results showed that the degree of deacetylation and molecular weight of chitosan were 72.93% and 788805 respectively. The biomembranes have good elongation and tensile strength. pH of biomembranes were 4. 68±0. 0 1-5. 30±0. 06. Its were stable in stored at cold temperature (5 °C) and became unstable after being stored for 3 days in ambient temperature. The concentration of chitosan solution did not significanf influence the elongation and tensile strength of the biomembrane statistically (P>O. 05).
Keywords : Citosan, elongation, tensile strength, biomembrane.

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Series Title

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Call Number

FARMASAINS : Jurnal Ilmiah Ilmu-ilmu Kefarmasian,

Publisher

Jakarta : Jurusan Farmasi Uhamka Jakarta., 2012

Collation

7p

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ISBN/ISSN

2086-6968

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Subject(s)

wound healing
CHITOSAN

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