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The correlation between the intensity of benzene exposure and complete blood count in the oil and natural gas company workers in East Kalimantan

Idha Arfianti Wiraagni - Nama Orang; Iwan Dwiprahasto - Nama Orang; Ngatidjan - Nama Orang;

Benzene is one of the dangerous chemical substances which can cause some health disturbances. Meta-analysis shows th at people who are exposed to benzene have a leukemia risk of 1.4 times more than the ones who are not. The employees who are exposed to benzene for a long time have a probability to receive the toxic effect from benzene. This study was conducted to eva lu ate the relationship between the intensity of benzene exposure and blood count of employees in the oil and natural gas company in East Kalimantan.
This research was conducted to 897 employees with case control design. The control group consisted of 521 subjects, whereas the case group consisted of 376 subjects. The subjects were 39.91 ± 10.90 years old, with the working term between 1 to 36 years. Data were obtained from routine medical check-up and health risk assessment in 2007 - 2010. The independent variable namely benzene exposure and the dependent variable namely result of blood count, were analyzed by using chi-square bivariat analysis. Intensity of benzene exposure was measured as OVM (Organic Vapour Monitor) for external dosage and SPMA (S-phenylmercapturic acid) for internal dosage. The intensity of benzene in 2007 was 1.07± 5.5 ppm (OVM) and average of SPMA was 11.54±5.28 19/9 creatinine. The intensity of benzene in 2009 was 4.15±13.6 ppm (OVM) and SPMA was 55.90±43.6 19/9 creatinine. The employees who were ex pos ed to benzene had a risk of having a decrease of either hemoglobin, erythrocyte, thrombocyte, or leukocyte 1.71 times (95% CI, 1.18-2.48) compared with the control, although this reduction was still in the normal range (p = 0.004). In conclusion, there was no relationship between the intensity of benzene exposure with the low blood count of the employees.


Ketersediaan
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Belum memasukkan lokasi Journal of The Medical Sciences, 44 (1) 2012 : 99-
A0003285
Tersedia
Informasi Detail
Judul Seri
-
No. Panggil
Journal of The Medical Sciences, 44 (1) 2012 : 99-
Penerbit
Yogyakarta : FK Universitas Gajah Mada Yogyakarta., 2012
Deskripsi Fisik
12p
Bahasa
ISBN/ISSN
0126-1312
Klasifikasi
-
Tipe Isi
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Tipe Media
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Tipe Pembawa
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Edisi
-
Subjek
BENZENE
BLOOD CELL COUNT
Info Detail Spesifik
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Pernyataan Tanggungjawab
-
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Perpustakaan dan Galeri Kebijakan Kesehatan BKPK merupakan pusat informasi dan referensi dalam bidang kebijakan pembangunan kesehatan di Indonesia. Sebagai bagian dari upaya mendukung pengambilan keputusan berbasis bukti, kami menyediakan berbagai koleksi literatur ilmiah, laporan kebijakan, jurnal, buku, serta sumber daya digital lainnya yang relevan dengan sektor kesehatan.

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