Korelasi Jumlah Cd4 Dan Total Lymphocyte Count (Tlc) Pada Penderita HIV/AIDS Dengan dan Tanpa Terapi Antiretroviral (Correlation of Cd4 And The Total Number of Lymphocyte Couft (TLC) In HIV/AIDS Patients With And Without Antiretroviral Therapy) | Perpustakaan Badan Kebijakan Pembangunan Kesehatan

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Korelasi Jumlah Cd4 Dan Total Lymphocyte Count (Tlc) Pada Penderita HIV/AIDS Dengan dan Tanpa Terapi Antiretroviral (Correlation of Cd4 And The Total Number of Lymphocyte Couft (TLC) In HIV/AIDS Patients With And Without Antiretroviral Therapy)

Ivana Agnes Sulianto - Personal Name; Rudi Wisaksana - Personal Name; Agnes Rengga Indrati - Personal Name; Noormartany - Personal Name;

CD4 count is a marker for initial and follow up antiretroviral therapy (ART) in HIV/AIDS patients. It requires expensive equipment and skill to performed. World Health Organization (WHO) recommends total Iymphocyte count (TLC) as a substitute marker for CfJ4 count to start ART. The aim of this study was to evaluate the correlation between CD4 count and TLC in baseline and follow up data as a guide for follow up therapy. This study was an analytical observational study of HIV/AIDS patiens data in dr. Hasan Sadikin Hospital. It was part of IMPACT (Integrated Management for Prevention And Care and Treatment of HIV/AIDS) studt. The sampel of 2239 was divided into non ART AND ART groups. The data was analyzed using correlation analysis.
The result showed that the correlation between CD4 and TLC at baseline in male without ART was 0.644 (p=0.01), female without ART was 0.74 (p=0.01), male with ART is 0.67 (0.01), and female with ART was 0.601 (p=0.601). The correlation between CD4 and TLC at first follow up in male without ART was 0.0.56 (p=0.01), female with ART was 606 (p=0.01), male with ART was 0.569 (p=0.01), female with ART was 0.466 (p=0.01). The correlation between CD4 and TLC at second follow up in male without ART was 0.697 (p=0.01), female without ART was 306 (p=0.01), male with ART was 0.556 (p=0.01), female ART was 0.561 (p=0.01).
Conclusion : There was a good correlation between CD4 count and TLC so that TLC can be used as an alternative marker for follow up thwrapy.
Key word : HIV/AIDS, CD4 count, total lymphocyte count, antiretroviral therapy

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Location name is not set Global Medical Health & Communication : Journal of

A0003259

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Series Title: -
Call Number: Global Medical Health & Communication : Journal of
Publisher: Bandung : FK Universitas Islam Bandung., 2012
Collation: 5p
Language
ISBN/ISSN: 2301-9123
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Subject(s): HIV
lymphocytes
AIDS
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