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Leukemia Myeloblastik Akut : Luaran Terapi di RSUP DR. Sardjito, Yogyakarta, 2004-2008

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Background The incidence of childhood acute myeloblastic leukemia (AML) had increased for years, but the success of therapy is still low. Objective To analyze overall survivel (OS) and prognostic factors of AML in Dr. Sardjito General Hospital from January 2004 -December 2008. Methods Patients aged less than 15 years and newly diagnosed as AML included in this study. The prognostic factors such as WBC and nutritional status were recorded. The 05 was analyzed using Kaplan-Meier method. Prognostic factors were analyzed using Cox regression.
Results of 56 (63.6%) patients underwent chemotherapy with a modified NOPHO-AML 93 protocol, 19 patients (33.9%) were died, 4 (7%) were relapsed, 32 (57%) were dropped out, and 1 (2%) was sutvived. Median survive! was 3.05 months (10 days - 2.8 years), 3-year overall survivel was 19 ± 10%. Conclusion Childhood AML still have poor prognosis in our institution. Progression of disease, drug toxicitv: and insufficient supportive care may ca use this condition.
Keyword: childhood AML, prognostic factors, overall survival

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Series Title

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Call Number

Indonesian Journal of Cancer, 7 (2) 2012 : 49-52

Publisher

Jakarta : "Dharmais " Cancer Hospital Jakarta., 2012

Collation

4p

Language

ISBN/ISSN

1978-3744

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Carrier Type

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Edition

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Subject(s)

LEUKIMIA, MYOLOCYTIC, ACUTE-THERAPY

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