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Hematoma Subdural Pada Bayi Dengan Acquired Prothrombine Complex Deficiency (Aped) Syndrome Di Rs. Hasan Sadikin Dari Juli 2010 Sampai Februari 2011 (Subdural Hematoma In Neonates With Acquired Prothrombine Complex Deficiency (APCD) Syndrome At Hasan Sadikin Hospital From July 2010 Till February 2011)
Background and Objective: APCD syndrome is one of the most serious diseases ajJecting nfants. It leads to a high mortality rate and permanent neurological sequelae among the survivors when related with SDH There are reports about high prevalence of using herb-liquor extracts and diet restriction among mothers of infants with the APCD syndrome. Vitamin K2MK4 levels in breast milk obtained from mothers who had used herb-liquor extracts were lower than vitamin K2MK4 levels in breast milk obtained from mothers who had not us ed herb-liquor extracts.
Subject and Method: Six infant cases which diagnosed with spontaneous SDH due to APCD syndrome, reviewed from July 2010 to February 2011 at Hasan Sadikin Hospital Bandung. Data reviewed include history taking, physical examination, CT-scan results, laboratory results, management and findings during operation
Result: All six infants showed evidence of having history, sign and symptoms, and bleeding disorder suggesting SDH due to APCD. Management on all cas es above included early CT-scan evaluation, the treatment of APCD and immediate surgical intervention resulted on good outcome on post surgery result and hospital disposal
Conclusions: Prolonged coagulation factors on all cases suggest higher risk for APCD on the infant. Craniotomy evacuation surgery less than 3 days interval from onset immediately gave better outcome on Children Coma Scale (CSS) score.
Key Words: acquired prothrombine time complex disorders, subdural hematoma, neurosurgery, neuroanesthesia
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