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Elastin Expression in Sacrouterina Ligament is Weaker in the Women with Pelvic Organ Prolapse

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Abstract Objective: The research aims at comparing the elastin immunolabelingin the uterosacral ligaments in women with pelvic organ prolapseand without pelvic organ prolapse (POP).Methods: The research is done at Dr. Wahidin Sudirohusodo Hospitaland education networking some hospitals the Obstetrics and GynecologicalSchool of Medicine Hasanuddin University that began inJanuary 2011 until April 2012. This research assessing expression ofelastin on 35 women with a pop level III and IV and as control is 35women without POP. Immunolabeling of elastin valued in stainingcheckings immunohistokimia uses antibodies elastin ( clone no. Ba-41:1600; Novacastra Laboratories Ltd, UK). The research was carriedout by the cross sectional study. Mixed with chi-square. Level significanceused is 0.05.Results: The results showed that the elastin immunolabeling inwomen with POP is decline on most sample expression with the intensityof elastin is weak (74.3%). The most control with the intensityof elastin immunolabeling is moderate (48.6%). Elastin immunolabelingseem significant in women with menopause and withBMI that overweight (all with p

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Indonesian Journal of Obstetrics and Gynecology, 3

Publisher

Jakarta : Indonesian Society of Obstetrics and Gynecology., 2012

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5p

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0303-7924

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