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Moderate-Severe Endometriosis Shows Higher CA-125 Serum Level Compared to Minimal-Mild Endometriosis

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Abstract Objective: To investigate and compare serum profile of CA-125, erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) in various stages of endometriosis.Methods: Forty endometriosis patients’ blood samples were taken prior to laparoscopic surgery for various indications. Diagnosis of endometriosis was confirmed by laparoscopy. Independent T test methods were used for statistical analysis. ROC analysis was examined for each variable.Results: The mean level of CA-125 serum was 12.0 vs. 36.3 U/ml (p < 0.05); ESR serum was 11 vs. 12.8 mm/hour (p > 0.05); CRP serum was 0.7 vs. 0.3 (p > 0.05) for endometriosis stage I-II and stage III-IV, respectively. The optimal cut off point to discriminate endometriosis stage I-II and III-IV was 16.9 U/ml with sensitivity 83% and specificity 81%.Conclusion: The CA-125 serum level was increased for moderatesevere endometriosis compare to minimal mild endometriosis patient. 121-4]Keyword: CA-125, CRP, endometriosis, ESR, serum

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Series Title

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Call Number

Indonesian Journal of Obstetrics and Gynecology, 3

Publisher

Jakarta : Indonesian Society of Obstetrics and Gynecology., 2012

Collation

4p

Language

ISBN/ISSN

0303-7924

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Edition

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Subject(s)

endometriosis
SERUM

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