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High Level of Tumor Necrosis Factor (TNF)-α is a Risk Factor for Preeclampsia

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Abstract Objective: To define that elevated TNF-α serum level was the risk factor of reeclampsia in pregnancy. Method: This research is a case-control study. From 56 pregnant women, there are 28 women with preeclampsia and the other 28 women with normal pregnancy. Then the serum level of TNF-α was obtained at Prodia’s clinical Laboratory Denpasar. Data’s normality test was done with Kolmogorov-Smirnov, then an analysis of data was done with Independent Sample Test, predictive value a = 0.05. To define the role of TNF-α level in preeclampsia, Chi-Square test was chosen.

Result: From this research we found the average level of TNF-α in preeclampsia (6.64 ± 7.64 pg/ml) was higher than in normal pregnancy (2.42 ± 1.77 pg/ml). Analysis with t-independent test shows that the t-value was 2.85 and p-value was 0.006, which means that the average level of TNF-α between the two group was significantly different (with predictive value, p

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Series Title

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Call Number

Indonesian Journal of Obstetrics and Gynecology, 3

Publisher

Jakarta : Indonesian Society of Obstetrics and Gynecology., 2012

Collation

5p

Language

ISBN/ISSN

0303-7924

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Carrier Type

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Edition

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Subject(s)

pre-eclampsia
TUMOR NECROSIS FACTOR-ALPHA

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