Text

Patofisiologi dan Marker Airway Remodeling pada Asma Bronkial (Pathophysiology and Markers of Airway Remodeling in Brochial Asthma)

---

Asthma is a cronic inflammatory disease characterized by reversible airflow limitatison and airway hyperresponsiveness. Persistent inflammation in airway tissues may lead to structural changes known as airway remodeling and consequently airway obstruction that is not fully reversible and progressive loss of lung fungtion over time. In asthma, airway structural changes include subepithelial fibrosis, increased smooth muscle mass, enlargement on glands, neovascularization, and epithelial alterations. A number of markers have been and are being considered as noninvasive markers of airway remodeling, including airway smooth muscle, eosinophil count and serum ECP, TGF-B1, MMP-9, VEGF, serum tryptase, mucin and MUC genes, ADAM33, and fungtional markers : FEV1/FVC and airway distensibility (AVD)

---

Availability

Detail Information

Series Title

-

Call Number

Jurnal Respirologi Indonesia, 32 (2) 2012 : 110-11

Publisher

Jakarta : Perhimpunan Dokter Paru Indonesia (PDPI)., 2012

Collation

10p

Language

ISBN/ISSN

0853-7704

Classification

-

Content Type

-

Media Type

-

Carrier Type

-

Edition

-

Subject(s)

asthma
lung diseases, obstructive
AIRWAY OBSTRUCTION

Specific Detail Info

-

Statement of Responsibility

-

Other version/related

File Attachment

Comments

---

You must be logged in to post a comment