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Patofisiologi dan Marker Airway Remodeling pada Asma Bronkial (Pathophysiology and Markers of Airway Remodeling in Brochial Asthma)

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Asthma is a cronic inflammatory disease characterized by reversible airflow limitatison and airway hyperresponsiveness. Persistent inflammation in airway tissues may lead to structural changes known as airway remodeling and consequently airway obstruction that is not fully reversible and progressive loss of lung fungtion over time. In asthma, airway structural changes include subepithelial fibrosis, increased smooth muscle mass, enlargement on glands, neovascularization, and epithelial alterations. A number of markers have been and are being considered as noninvasive markers of airway remodeling, including airway smooth muscle, eosinophil count and serum ECP, TGF-B1, MMP-9, VEGF, serum tryptase, mucin and MUC genes, ADAM33, and fungtional markers : FEV1/FVC and airway distensibility (AVD)

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

Jurnal Respirologi Indonesia, 32 (2) 2012 : 110-11

Penerbit

Jakarta : Perhimpunan Dokter Paru Indonesia (PDPI)., 2012

Deskripsi Fisik

10p

Bahasa

ISBN/ISSN

0853-7704

Klasifikasi

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Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

asthma
lung diseases, obstructive
AIRWAY OBSTRUCTION

Info Detail Spesifik

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Pernyataan Tanggungjawab

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Versi lain/terkait

Lampiran Berkas

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