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Efficacy of Various Topical Agents to Prevent Enamel Demineralization

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Backgrown: Enamel demineralization is a common and undesirable side effect of fixed appliance Orthodontic treatment. Many studies showed that the prevalence varied between 2-96%. There are many was to prevent demineralization and increased remineralization such as oral hygiene instruction and by topical application such as acidulated phosphate flour (APF) casein phospopeptide-amorphous calcium phosphate (CPP-ACPF). Purpose: The purpose of this in-vitro study was to evaluate the efficacy of various topical agents to prevent enamel demineralization. Methods: Fourty extracted human premolars were allocated to 1of 4 groups: 1.23% APF gel: 10% CPP-ACP paste: 10% CPP-ACPF paste: and untreared control. All samples were subjected to pH cycling treatment for 12 days throuht a daily procedure of demineralization solution with pH 4 for 6 hours and and remineralization solution with pH 7 for 18 hours. Microhardenes testing were done before and after pH cycling and the delta hardness value compared with untreated control group. Kruskal-Wallis. ANOVA. Mann-withney U. Tukey and Bonferroni Post-Hoc multiple comparison test showed significant difference between mean delta microhardeness value of CPP-ACPF and CPP-ACP group with APF group, but there is no significant difference between delta microhardeness value of CPP-ACPF and CPP-ACP group. conclusion: APF,CPP-ACPF prevent enamel demineralization. CPP-ACP and CPP-ACPF prevent demineralization more than APF.

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Series Title

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Call Number

Dental Journal, 44(3)2011:141-144

Publisher

Surabaya : Airlangga University Press., 2011

Collation

4p

Language

ISBN/ISSN

1978-3782

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Edition

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Subject(s)

dental enamel
TOOTH DEMINERALIZATION

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