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The effect of spirulina gel on fibroblast cell number after wound healing process

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Background: Wound healing treatment after tooth extraction should be an important consideration due to mouth discomfort and pain. Spirulina (blue green algae) consists of C-phycocyanin, b–carotenoids, vitamin E, zinc, some other trace elements and natural phytochemical which are believed to act as antioxidant and takes part in wound healing process. Purpose: The purpose of this study was to examine the effect of spirulina gel on fibroblast cell number after wound healing process. Methods: Twenty eight males guinea pig are devided into four group, 7 guinea pig each. They are control group and treatment group which is given 0%, 3%, 6%, and 12% spirulina gel. After tooth extraction, histopathological evaluation was done to count fibroblast cell. The data was analyzed by One-Way ANOVA and Tukey HSD. Results: The research has proven the relation between the increased growth of fibroblast cell and spirulina gel application. The higher the doses, the more cell growth. Hence, there has been significant different (p < 0.05) among groups. Conclusion: Spirulina gel increases the number of fibroblast in wound after tooth extraction and 12% spirulina gel has the most potential ability.

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Detail Information

Series Title

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Call Number

Dental Journal Majalah Kedokteran Gigi, 44 (4) 201

Publisher

Surabaya : Airlangga University Press., 2011

Collation

3p

Language

English

ISBN/ISSN

1978-3728

Classification

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Content Type

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Media Type

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Carrier Type

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Edition

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Subject(s)

wound healing
fibroblasts
SPIRULINA

Specific Detail Info

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