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The effectiveness of Nigella sativa seed extract in inhibiting Candida albicans on heat cured acrylic resin

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Background: Indonesia has a variety of plants that can be used for medicines. One of the medicinal plants is Nigella sativa. Nigella sativa has been used for medicinal purposes, both as medicinal herb and as medicinal oil. It contains saponin and atsiri oils that have antifungal, antimicrobial and antibacterial effects. Nigella sativa has been suggested as denture cleansers since it can inhibit the growth of Candida albicans (C. albicans) on heat cured acrylic resin. Purpose: The aim of this research is to know the effectiveness of Nigella sativa seed extract in inhibiting the growth of C. albicans on heat cured acrylic resin. Methods: Eighteen acrylic samples were divided into three groups. Group I was control group, only
contaminated with C. albicans without immersing in any solution. Group II was acrylic sample immersed in sterile aquades for one hour. Group III was acrylic sample immersed in Nigella sativa seed extract for one hour. Results: There were significant differences of C. albicans (p < 0.05) among the three groups.
The number ofCandida albicans was significantly higher in Group I, while that in group II was lower than that in group I, and that in group III was the lowest. Conclusion: Nigella sativa seed extract was effective in inhibitin the growth of C. albicans on heat carred acrylic resin.

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Detail Information

Series Title

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Call Number

Dental Journal,44(3)2011:137-140

Publisher

Surabaya : Airlangga University Press., 2011

Collation

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Language

English

ISBN/ISSN

1978-3728

Classification

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Content Type

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Media Type

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Carrier Type

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Edition

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Subject(s)

CANDIDA ALBICANS
NIGELLA SATIVA
ACRYLIC RESINS

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