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PERBANDINGAN SENSITIVITAS AMPISILIN TERHADAP Klebsiella sp. PENGHASIL EXTENDED SPECTRUM BETALACTAMASE (ESBL) DAN NON ESBL PADA KATETER
Klebsiella sp.’s infection has been a serious problem as catheter associated urinary tract infection at hospital. Klebsiella sp.’s resistance to ampicillin has been found 100 % in Indonesia and it is caused by a new strain of bacteria which can produce SHV, CTX-M and PER type Extended Spectrum Betalactamase(ESBL). The study was to know ampicillin’s sensitivity between Klebsiella sp. as ESBL and non ESBL
producer which cause nosocomial infection. Specimen taken from patients that used urinary catheter for two days in surgical and intensive care unit. ESBL examination was done by Initial Screen Test and ampicillin’s sensitivity test was Disk Diffusion Test. The statistic analysis was chi-square and the alternative test was Kolmogorov
- Smirnov. There were 50 samples but only 19 samples which were Klebsiella sp. positively. The sensitivities of ampicillin to Klebsiella sp. as ESBL producers
were 6.7% for sensitive, 0% for intermediate and 93.3% for resistance. Ampicillin’s sensitivities to Klebsiella sp. as non ESBL producers were 25% for sensitive, 50% for intermediate and 25% for resistance. The statistic analysis’s result showed that there was no difference between Klebsiella sp. as ESBL and non ESBL producer at catheter urinary with asymp. Sig.(2-tailed) was 0.105. This study concluded that proportionally, ampicillin was more sensitive to Klebsiella sp. as non ESBL than ESBL producer at catheter urinary but statistically, there was no difference between
Klebsiella sp. as ESRL and non ESRL producer in urinary catheter.
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