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Pengaruh Pb-asetat terhadap Berat dan Volume Testis Mencit Effect of Pb-acetate on Testicle Weight and Volum of Mice
Background: The human effort to meet the needs of human life is almost always cause pollution in theenvironment of his life. One of the pollutants that harm human beings are lead (Pb = plumbum), Pb is one ofthe heavy metals that are harmful to health. Pb may also affect the reproductive organs. The purpose of thisstudy to determine the effect of Pb-acetate on mouse testis weight and volumeDesign and Method: Eighty male mice placed in individual cages according to the group. Food and drinkprovided ad libitum. The treatment of male mice given for 6 weeks. Treatment with 0.2 ml distilled water toPI, P II were given a solution of 400 ppm Pb acetate total of 0.2 ml, P III was given a solution of 1000 ppm Pbacetate as many as 0.2 ml, and P IV were given a solution of 2000 ppm Pb acetate total of 0,2 ml by usinga gastric sonde, every morning once a day for 42 days. At week 7, mice were surgery to take the testis.Testicular volume was measured and weighed. Data were analyzed by ANOVA, hypothesis is accepted whenp 0.05), testis weight obtained by ANOVA testprobability of 0.216 (> 0.05), mean Pb -acetate had no effect on testis weight and volume.Conclusion: Pb-acetate had no effect on testis weight and volume ).
A0002350 | Sains Medika:3(2)2011:150-156 | Available |
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