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Indeks Daya Fagosit Makrofag Peritoneum Setelah Pemberian Propolis Pada Mencit (Mus musculus) Phagocytic Index of Peritoneal Macrophages after Propolis Suplementation in Mice (Mus musculus)

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Background: Various diseases depend on individual’s immunity. Many of which nowadays have not had theeffective and formal therapy that makes experts researches the best and the most effective way for it; the useof Propolis as immunomodulator is one of them. This research aims for knowing the effect of propolis towardsperitoneal macrophage phagocytic index on mice.Design and Method: This research is an experiment with post test study design randomized control groupdesign. This study used mice that were divided into four groups randomly. The first group / Group-I were fornegative control (standard feed and aquadest); The second group/Group-II were fed standard-feed, aquadest,and propolis at a dose of 1.25 mg/kgBM; the third group/group-III were fed standard-feed, water, and propolisat a dose of 2.5 mg/KgBM; The fourth group/Group-IV were fed standard feed, water, and propolis at a doseof 5 mg/KgBM. Treatment where conducted for 3 days.Result: The average macrophage phagocytic index, were at the highest level of it (7.82 1.63) while the lowestone were the first group 3.43 0.13. The Kruskall Wallis result stated that there is index difference amongvarious groups with p 0.002 (p < 0.05).Conclusion: Propolis effected on mice peritoneal macrophage phagocytosis index (Sains Medika, 3(2):121-128).

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Sains Medika:3(2)2011:121-128

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Semarang : FK. Universitas Islam Sul Agung Semarang., 2011

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7p.

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2085-1545

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