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Pengaruh Tempe terhadap Kemampuan Fagositosis Makrofag Studi Eksperimental pada Mencit Jantan Strain Balb/c

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Background: Consuming tempeh regularly increases the levels of isoflavones in the our body influencing the IFNγ and macrophage activating factor (MAF) that lead to the in increase in the ability of macrophage phagocytosis. Macrophage phagocytosis gives an illustration of the macrophages ability as the first line of phagocytic cells to digest foreign particles. This study aims at finding out the influence of tempeh on the ability of macrophage phagocytosis. Design and Methods: In an experimental study using post test only control group design, 15 mice Balb/
c were divided into 3 groups of 5 mice each. Gp1: 0.5 gr of tempeh juice, Gp2: 1 mg tablet imboost in 1 cc of water (positive control), Gp3: 1 cc of 1 times (negative control). Treatment was given daily for 12 days. On day 13, Phagocytic ability of macrophages were examined using latex beads method. Data were analyzed using one Kruskal Wallis test followed by Independent T-Test. Results: The phagocytic ability for the three groups were 760,6 -----± 109,898 ; 244.2 ± 70.159; 9.6 ± 2.839
respectively. Independent t- test resulted in the significance difference (p = 0.008) between treated groups and control groups, both positive and negative ones (p

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Detail Information

Series Title

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Call Number

Sains Medika,3(1)2011:54-62

Publisher

Semarang : FK. Universitas Islam Sultan Agung Semarang., 2011

Collation

8p.

Language

ISBN/ISSN

2085-1545

Classification

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Content Type

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Media Type

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Carrier Type

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Edition

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Subject(s)

RATS, INBRED STRAINS
MACROPHAGES
PHAGOCYTOSIS

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