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Efikasi Kombinasi Rabamipide dengan Lansoprazole pada Proses Penyembuhan Tukak Lambung Tikus yang Dipapar Indometasin

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Erre radicals in cigarette smoke was known could promote infertility. Fee radicals activity can be inhibited by antioxidant in black seed (thymoquinane, nogelllone, carvvacrol, t-anethole, and 4 terpineol). The aim of this study was to assess the effect of black seed extract on MDA concentration in testis and spermatogonium cell number in subacute nonfilter-tipped cigarette smoke exposed rats. The MDA concentration in testis and spermetogonium cell number was the indicator of testicular damage caused by free radicals activity. This experimental study using 20 male Wistar strain (Rattus norvegicus) which randomly divided into five groups, as follows, the control group, the control positive group, the first, the second, and the third treatment groups (exposed to nonfilter-tipped cigarette smoke and treated with block seed extract 0,6;1,2;2,4 g/BB/day subsequently). The MDA concentration in testis was measured by Thio Barbitueic Acid test methode. Testis made into histopathologycal prreparation using Haematoxcylin Eosin (HE) staining, for counting the spermatogonium cell number. It could be condluded that block seed antioxidant activity to prevent decreasing spermatogonium cell by inhibit lipid peroxida caused by subacute nonfiter-tipped cigarette smoke exposure

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Judul Seri

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No. Panggil

Jurnal Kedokteran Brawijaya:26(3)2011:166-170

Penerbit

Mataram : F. Universitas BrawijayaK., 2011

Deskripsi Fisik

4p.

Bahasa

ISBN/ISSN

0216-9247

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Tipe Media

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Tipe Pembawa

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