Expression of Matrix Metalloproteinase-8 Gene in Fixed orthodontic Patients | Perpustakaan dan Galeri Kebijakan Kesehatan

Pencarian berdasarkan :

SEMUA Pengarang Subjek ISBN/ISSN Pencarian Spesifik

Pencarian terakhir:

Text

Expression of Matrix Metalloproteinase-8 Gene in Fixed orthodontic Patients

Susilowati - Nama Orang; Mansjur Nasir - Nama Orang; Imam Mudjari - Nama Orang; Thalca Hamid - Nama Orang;

Background: Orthodontic treatment with fixed apliance produces structural and biochemical changes and breeding the balance between the synthesis and the breakdown of the collagen in the periodontium. Matrix metalloproteinase-8 (MMP-8) plays an importantrole in the remodeling of periodontal ligament during orrhodontic movement. Purpose: The purpose of this study was to observe the expression MMP-8 gene in the singival cervicular fluid (GCF) of fised orthodontic patients. It is expexted that the result can be used as a reference to decide the proper time for clastomeric chain to be reactivated. Methods: Orthodontic fixed appliances were placed on 8 patients and clatomeris chains exerting 75 grams were atached to produce camine distalization. GCF samples were collected from the distal side of upper canines before force application, 1.2.3-and4 weeks after application consecutively. The samples were analyzed by using RT-PCR. Statistical analyses used were univariate analysis and Mann-Whitney U test. Result: The expression of MMP-8 in the GCF at t0 was 31.3% but the foce application elevated its expression to 65.6% at t₁, and then decreased continously at t2,t3,t4. There was no statistically significant difference of MMP-8 gene expression betwen t0 and t3. Conclusion; The highers level of MMP-8 gene expression due to orthodontic forces was occured in the first week, but it declined continously in the following weeks. The proper time to reactivate an elastomeric chain was 3 weeks after application.

Ketersediaan

Belum memasukkan lokasi Dental Journal:44(1)2011:54-58

A0002283

Tersedia

Informasi Detail

Judul Seri: -
No. Panggil: Dental Journal, 44(1)2011:54-58
Penerbit: Surabaya : Erlangga University Press., 2011
Deskripsi Fisik: 4p.
Bahasa: English
ISBN/ISSN: 1978-3728
Klasifikasi: -
Tipe Isi: -
Tipe Media: -
Tipe Pembawa: -
Edisi: -
Subjek: orthodontics
PATIENTS
MATRIX METALLOPROTEINASE 8
Info Detail Spesifik: -
Pernyataan Tanggungjawab: -

Versi lain/terkait

Tidak tersedia versi lain

Lampiran Berkas

Tidak Ada Data

Komentar

Anda harus masuk sebelum memberikan komentar