Text

Mekanisme Resistens Kortikosteroid Pada Asma

---

Asthmatic patients have a specific patterm of airway inflamation that underlies the clinical features. Corticosteroids known to be useful for controling asthma and have a mojor effect in reducting inflammation of the airway well, suppress the expression of various genes in the airway inflamation and repair the bronhial hyperresponsiveness. However, a few asthmatic patients show a poor or absent response even to high doses of corticosteroid Knowing the mechanisms of carticosteroids resistence in asthma may lead to provide a better understanding on the management of corticosteroid resistant asthma. Molecular mechanisme of corticosteroid resistance include abnormalities in ligand binding and transiocation of the nucleus, decreased expression and or co-respressor protein activity or increased expression of inflammatory transciption factors

---

Availability

Detail Information

Series Title

-

Call Number

Jurnal Respirologi Indonesia, 31 (4) 2011 : 210-22

Publisher

Jakarta : Perhimpunan Dokter Paru Indonesia., 2011

Collation

13p.

Language

ISBN/ISSN

0853-7704

Classification

-

Content Type

-

Media Type

-

Carrier Type

-

Edition

-

Subject(s)

asthma
adrenal cortex hormones

Specific Detail Info

-

Statement of Responsibility

-

Other version/related

File Attachment

Comments

---

You must be logged in to post a comment