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Perbandingan Efek Analgesia Deksketoprofen Trometamol dengan Ketorolak sebagai Preventif Analgesia pada Anestesi Umum

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Postoperative pain is one of the most important problems that follows the surgery process, which leads to the need of potent analgesic drugs during the postoperative period. NSAIDs are prominent as analgesics because they can decrease the need of opioids and the rate of inflmmatory mediators but do not cause sedation. The purpose of this research is to compare the analgesic effects of Dexketoprofen trometanol and Ketorolac as preventive analgesic during general anaesthesia. After obtaining permission from FK USU ethics committe, 64 samples of reearch were collected, men and women who were in the indusive criteria and underwent elective surgeries at COT RSUP HAM Medan under general anaestesia. Samples were divided into 2 groups randomly, each with 32 subjects. Thirty minutes before the first cut. Group A was given Dexketoprofen trometamol 50 mg/iv dan group B was given kerorolac the first cut. Group A was given Dexketoprofen trometamol 50 mg/iv dan Group B was given ketorolac 30 mg, and general anesthesia procedures were continued. VAS data was observed in the postoperantive period of both groups, by asking the patients to show their pain intensity on the VAS assessment card. The result was assessed from 0 (no pain) to 10 (terrible pain) from the first 8 hours till the sixth 8 hours VAS results that were obtained after the administration of analgesics showed significant diffferences in both groups. The result of the research repeatedly using the T-test showed p=0.004, p=0.001, p=0.000, p=0.005, p=0.013, p=0.003. The results of the research shows tht there is a significant difference between both groups statistically. Patients who were administered Dexketoprofen trometamol showed a lower VAS score, onset of action being faster compared to Kotorolac dan both drugs can be used at prevention analgesia.

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Judul Seri

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No. Panggil

Medika;37(4)2011:240-249

Penerbit

Jakarta : PT. Grafiti Medika Pres., 2011

Deskripsi Fisik

9p.

Bahasa

ISBN/ISSN

0216-0910

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Tipe Media

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