Pengaruh Diet Madu terhadap Gambaran Mikroskopis Pulpa Putih Lien Mus musculus yang Diinfeksi dengan Pseudomonas aeruginosa | Perpustakaan Badan Kebijakan Pembangunan Kesehatan

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Pengaruh Diet Madu terhadap Gambaran Mikroskopis Pulpa Putih Lien Mus musculus yang Diinfeksi dengan Pseudomonas aeruginosa

Harapan - Personal Name; I. Badiri - Personal Name; Z. Hayati - Personal Name; M.A. Sabisi - Personal Name; L. Fathiarini - Personal Name; S.E. Lubis - Personal Name;

The honey is known by people as a medicine for threatment several deseases, but until now the used of honey has not naximun jet . The purpose of this research is to determine the effect of honey on microscopic appearance of the white pulp part of spleen Mus musculus after infected by Pseudomonas aeroginosa. Research design used was posttest only control group design. Three groups of M. musculus strains DJ, male, 1.5 months were used four times each. Doses of honey given were 0.8 ml, 0.4 ml, and 0.2 ml per day for each group. Honey diet was conducted over 20 days. P. aeruginosa injected intraperitoneally into each animal with a single dose of 0.1 ml of 2 Mc Farland. M. musculus were incised and spleen histology preparations with HE dye were made, then diameters of the white pulp spleens were measured using a microscope by 100x magnification. From the research, there was no significant difference in the diameter of the white pulp spleen between group of 0.8 ml dose of honey and group of 0.4 ml dose of honey (p = 0.164.) There was significant difference of white pulp spleen diameter between group of 0.8 ml dose of honey and group of 0.4 ml dose of honey (p = 0.001). There are also significant difference of white pulp lien diameter between group of 0.4 ml dose of honey and group of 0.2 ml dose of honey (p = 0.000). These results showed that honey can improve the body’s immune system by increasing the activity of white pulp spleen of M. musculus. However, the mechanism can not be determined. Therefore, it’s necessary to determine the cellular and molecular mechanisms of how honey increases the body’s immune system.

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Location name is not set Medika;37(2)2011:92-97

A0002191

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Detail Information

Series Title: -
Call Number: Medika Jurnal Kedokteran Indonesia, xxxvii (2) 201
Publisher: Jakarta : PT. Grafiti Medika Pres., 2011
Collation: 5p.
Language
ISBN/ISSN: 0216-0910
Classification: -
Content Type: -
Media Type: -
Carrier Type: -
Edition: -
Subject(s): HONEY
MICROSCOPY
PSEUDOMONAS AERUGINOSA
Specific Detail Info: -
Statement of Responsibility: -

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