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Perbandingan Gambaran Urinalisis dan Tes Faal Ginjal Dengue Primer dan Sekunder

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Dengue Fever (DF) is still be a public health problem in Indonesia where primary DF usually gives less symptoms then secondary DF. The difference between primary DF and Secondary DF can be made by measuring of Ig G and Ig M level in patients’ blood specimen with Immunochromatography Dengue Fever Rapid Test (ICT-DFRT).
DF gives various abnormalities esuch as renal injury, creatinine increases, proteinuria, glomerulonephritis, hemolytic uremic syndrome. Proteinuria and abnormal urinary sedimen­t are the most common manifestations in DF. The objective of the study is to compare and observ­e the differences of urinalysis profiles and renal function in primary DF and secondary DF. Methods: Retrospective study was conducted using secondary data of medical records from some hospit­al in Malang during periods of January 2006 until February 2010. Primary DF and secondary DF were distinguished using Ig G & Ig M with ICT-DFRT. Secondary DF was divided into group 1: positive Ig G and Ig M, and group 2: positive Ig G but negative in Ig M, while primary DF (group 3) was derived from positive Ig M only. Urine examination was conducted using dipsticks test & urinary sediment, renal functio­ns test was conducted using clinical chemistry auto analyzers. Results were analyzed using studen­t t test & ANOVA using SPSS 17 with degree of confidence p < 0,05.

Results: Laboratory test results shows a significant differences between group 1, 2, 3 in proteinuria (p 4 /pf) was 25.91%, 26.36%, 20%, and 25.96% respectively. Lekosituria (leucocytes count > 4/pf) was 24.03%, 25.45%, 25.37%, and 24.20% respectively. Creatinine serum shows significant difference only in I vs 2 groups (secondary dengue) with p = 0.024 (p < 0.05). Conclusion: There are significant differences in laboratory profiles betwe­en primary DF and secondary DF in proteinuria (p< 0,05). Negative proteinuria found higher in primary than secondary DF. Therefore, it is advised to perform urinalysis and renal function test if needed.

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

Medika:37(11)2011:746-751

Penerbit

Jakarta : PT. Grafiti Medika Pres., 2011

Deskripsi Fisik

5p.

Bahasa

ISBN/ISSN

0216-0910

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Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Pernyataan Tanggungjawab

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