Effect of Calcium Polystyrene Sulfonate on Potassium Decrease in Chronic Renal Failure Patients Untreated With Hemodialysis | Perpustakaan Badan Kebijakan Pembangunan Kesehatan

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Effect of Calcium Polystyrene Sulfonate on Potassium Decrease in Chronic Renal Failure Patients Untreated With Hemodialysis

Apen Afgani - Personal Name; Augusta Y. Arifin - Personal Name; Hadi Martakusumah - Personal Name; Rulli M. Roesli - Personal Name;

Hyperkalemia is a cathastrophic medical emergency, associated with its effect on the myocardium. This condition was reported in 1.1%-10% of patients admitted to hospital, with approximately on death per 1.000 case of hyperkalemia. Administration of calcium polystyrene sulfonate (CPS) has been proposed to be an effective method to treat hyperkalemia. This study aimed to evaluate the effect of CPS in lower serum potassium in non-hemodialyzed chronic kidney disease (CKD) patients.

This study was an open randomized clinical trial on 64 outpatients with CKD from Nephrology clinic Dr. Hasan Sadikin Hospital, Bandung. The subject were male and female older than 17 years old, diagnosed with CKD who had not been hemodialyzed. Exlusion criteria were digitals use, angiotensin converting enzyme-inhibitors, non steroid anti inflammatory drugs, a-receptor blockers, b-receptor blockers cyclosporine, diuretics, potassium-sparing diuretics, high-potassium diets, abnormal electrocardiograms, or a history of constipation or other bowel abnormality. The subject were divided into 2 groups, the first group were given CPS 3x5 gram daily for three days, while the second groups (control) were put on low-kalium diet for three days. Diets recall were done by a dietician before and after intervention.

The result were analyzed using dependent t-test for normally distributed data, before and after interventions, and using independent t test to comparison between study group and control. The potassium level before and after intervention were 5.07 (SD=0.33) and 4.32 (SD=0.34), respectively (p

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Location name is not set Medika:37(3)2011:174-179

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Series Title: -
Call Number: Medika:37(3)2011:174-179
Publisher: Jakarta : PT. Grafiti Medika Pres., 2011
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Language: English
ISBN/ISSN: 0216-0910
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