Prothrobin Time: Activated Partial Thromboplastin Time, Fibrinogen, dan D-Dimer prediktor Decompensated Disseminated Intravascular Coagulation Sisseminated pada Sepsis | Perpustakaan dan Galeri Kebijakan Kesehatan

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Prothrobin Time: Activated Partial Thromboplastin Time, Fibrinogen, dan D-Dimer prediktor Decompensated Disseminated Intravascular Coagulation Sisseminated pada Sepsis

Fenny - Nama Orang; Noormartany - Nama Orang; Ndjwa Zamalek Dilimoenthe - Nama Orang;

Sepsis is a systemic response to infection especially in pneumonia case. Sepsis can cause complications such as disseminated intravascular coagulation (DIC) which can be divided into compensated and decompensated DIC. The purpose of this study was to assess whether the value of prothrombin time (PT), activated partial thromboplastin time (aPTT), fibrinogen, and D-dimer levels can be used as predictors of decompensated DIC in sepsis patients. This study was conducted at the Laboratory of Clinical Pathology Rumah Sakit Hasan Sadikin Bandung since September 2008 to June 2010. Subjects were patients with sepsis caused by pneumonia. PT and aPTT values, fibrinogen, and D-dimer levels was recorded from all sepsis patients then patients were observed
until diagnosed decompensated or non-decompensated DIC, then the value of PT, aPTT, fibrinogen and D-dimer levels in the group of decompensated DIC and non-decompensated DIC were analysed. This study used cohort design. Subjects were 39 sepsis patients (58%) with outcome decompensated DIC and 28 sepsis patients (42%)
with outcome non-decompensated DIC. From the hemostasis parameter test out, it was found that PT, aPTT, and fibrinogen were the predictor of decompensated DIC in patients with sepsis with relative risk 240.500, 7.157, and 6.421; respectively. Conclusions, prothrombin time, aPTT, fibrinogen are the test to know coagulation activation. Hemostasis parameter to predict decompensated DIC in sepsis patients are the shorten PT, aPTT, and the increased fibrinogen. [MKB. 2011;43(1):49–54].

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Belum memasukkan lokasi Majalah Kedokteran Bandung: 43(1) 2011: 49-54

A0002053

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Judul Seri: -
No. Panggil: Majalah Kedokteran Bandung, 43 (1) 2011 : 49-54
Penerbit: Bandung : FK. Universitas Padjadjaran., 2011
Deskripsi Fisik: 5p.
Bahasa
ISBN/ISSN: 0126-074X
Klasifikasi: -
Tipe Isi: -
Tipe Media: -
Tipe Pembawa: -
Edisi: -
Subjek: Hemostatics
SEPSIS
PROTHOMBIN TIME
Info Detail Spesifik: -
Pernyataan Tanggungjawab: -

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