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Efek Antidiabetes Kombinasi Ekstrak Bawang Putih (Allium Sativum Linn) dan Rimpang Kunyit (Curcuma domestica Val) dengan Pembanding Glibenklamid pada Penderita Diabetes Melitus Tipe 2

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The combination of garlic (Allium sativum Linn.) and curcumin extract (Curcumma domestica Val.) can be used as an antidiabetic oral to type 2 diabetes mellitus (DM) patients and the clinical trial showed that the extract can decrease blood glucose at a dose 2.4 g/day. This clinical trial was conducted to know the antidiabetic effect of the combination of garlic and curcumin extract compared with antidiabetic oral, glibenclamide. The subjects were >35 years of age with type 2 DM who came to internal and endocrine clinic RSUP. Hasan Sadikin Bandung and has been treated with medical nutrition therapy for 2 weeks period November 2007–December 2008. The research design was parallel, randomized and double blind. The combination of garlic and curcumin extract decreased mean
value of fasting blood glucose 9.25 mg/dL, 2h PP blood glucose 22.25 mg/dL, HbA1c 1,30% and insulin 12.57 mg/ dL compared with baseline whereas glibenclamide decreased the mean value of fasting blood glucose 72.37 mg/dL, 2h PP 114,25 mg/dL, HbA1c 4.12% and increased insulin 3.34 mg/dL. In conclusion, the extract combination has antidiabetic effect eventhough the effect was not as high as glibenclamide. [MKB. 2011;43(1):26–34].

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Series Title

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Call Number

Majalah Kedokteran Bandung, 43 (1) 2011 : 26-34

Publisher

Bandung : FK UI., 2011

Collation

8p.

Language

ISBN/ISSN

0126-074X

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Media Type

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Carrier Type

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Edition

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Subject(s)

plants, medicinal
garlic
DIABETES MELLITUS, TYPE 2
Curcuma

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