Effect of Indonesia Medical Plants Essential Oils on Streptococcus Mutans Biofilm | Perpustakaan Badan Kebijakan Pembangunan Kesehatan

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Effect of Indonesia Medical Plants Essential Oils on Streptococcus Mutans Biofilm

Triana Hartiani - Personal Name; Dian Adityaningrum - Personal Name; Irami Duma Kencana Irianto - Personal Name; Sylvia Utami Tanjung Pratiwi - Personal Name;

Essential oil’s componenet such as menthol and eucalyptol were already used as dental plague inhibitors. In searching of potential dental plaque inhibitor from natural products, a study to explore the potency of essential oils extracted from several Indonesia medicinal plants against planktonic growth and biofilm adherence of S. Mutans was performed. A total of 14 essential oils from some selected Indonesianmedicinal plants were extracted by steam – hydro distillation. Antibacterial assay was performed against S. Mutans by micro dilution technique on nutrient broth. Biofilm formation inhibition assay was conducted on a flexible U-bottom 96-wells PVC micro by using BHI enriched with sucrose 2% at 36.6⁰C for 18-24 h. After astaining with 1% crystal violet, the optical density was read at 595 mm. A mouthwash commercial product containing essential oil component was used as a positive control. Result showed that the essential oils of C. Sintoc exhibited the highest blofilm formation inhibition (IC50 = 0.005%), and Z. Officinale showed the highest biofilm degradition with EC50 value of 0.013%. Both were active against bacterial planktonic growth but C.sintoc showed lower MIC50 value (0.%) in comparison to Z. Officinale (0.06%). Meantime, C ciratus was showed promising antibacterail and antibiofilm activities with MIC90 value of 0.06%, MBC 0.6%, IC50 0.008% and antibiofilm activites with MIC 90 value value of 0.06%, MBC 0.6%, IC50 0.008% and EC50 0.026%. It is concluded that the essential oils C. Citratus Z. Officinale and C. Sintoc are potential to be developed as dental plaque inhibitors.

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Location name is not set Majalah Farmasi Indonesia; 22(3)2011: 174-181

A0001950

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Detail Information

Series Title: -
Call Number: Majalah Farmasi Indonesia; 22(3)2011: 174-181
Publisher: Yogyakarta : Fakultas Farmasi UGM., 2011
Collation: 7p.
Language: English
ISBN/ISSN: 0126-1037
Classification: NONE
Content Type: -
Media Type: -
Carrier Type: -
Edition: -
Subject(s): plants, medicinal
PLANTS OILS
STREPTOCOCCUS MULANS
Specific Detail Info: -
Statement of Responsibility: -

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