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Effect of Indonesia Medical Plants Essential Oils on Streptococcus Mutans Biofilm

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Essential oil’s componenet such as menthol and eucalyptol were already used as dental plague inhibitors. In searching of potential dental plaque inhibitor from natural products, a study to explore the potency of essential oils extracted from several Indonesia medicinal plants against planktonic growth and biofilm adherence of S. Mutans was performed. A total of 14 essential oils from some selected Indonesianmedicinal plants were extracted by steam – hydro distillation. Antibacterial assay was performed against S. Mutans by micro dilution technique on nutrient broth. Biofilm formation inhibition assay was conducted on a flexible U-bottom 96-wells PVC micro by using BHI enriched with sucrose 2% at 36.6⁰C for 18-24 h. After astaining with 1% crystal violet, the optical density was read at 595 mm. A mouthwash commercial product containing essential oil component was used as a positive control. Result showed that the essential oils of C. Sintoc exhibited the highest blofilm formation inhibition (IC50 = 0.005%), and Z. Officinale showed the highest biofilm degradition with EC50 value of 0.013%. Both were active against bacterial planktonic growth but C.sintoc showed lower MIC50 value (0.%) in comparison to Z. Officinale (0.06%). Meantime, C ciratus was showed promising antibacterail and antibiofilm activities with MIC90 value of 0.06%, MBC 0.6%, IC50 0.008% and antibiofilm activites with MIC 90 value value of 0.06%, MBC 0.6%, IC50 0.008% and EC50 0.026%. It is concluded that the essential oils C. Citratus Z. Officinale and C. Sintoc are potential to be developed as dental plaque inhibitors.

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

Majalah Farmasi Indonesia; 22(3)2011: 174-181

Penerbit

Yogyakarta : Fakultas Farmasi UGM., 2011

Deskripsi Fisik

7p.

Bahasa

English

ISBN/ISSN

0126-1037

Klasifikasi

NONE

Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

plants, medicinal
PLANTS OILS
STREPTOCOCCUS MULANS

Info Detail Spesifik

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Pernyataan Tanggungjawab

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Versi lain/terkait

Lampiran Berkas

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